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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PFAS
All Species:
23.03
Human Site:
S873
Identified Species:
42.22
UniProt:
O15067
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15067
NP_036525
1338
144724
S873
T
A
L
A
Q
C
F
S
Q
L
G
E
H
P
P
Chimpanzee
Pan troglodytes
XP_511854
1397
150781
S932
T
A
L
A
Q
C
F
S
Q
L
G
E
H
P
P
Rhesus Macaque
Macaca mulatta
XP_001112405
1335
144369
S873
T
A
L
A
Q
C
F
S
Q
L
G
E
H
P
P
Dog
Lupus familis
XP_850167
1368
147436
S873
T
A
L
A
Q
C
F
S
Q
L
G
E
Q
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5SUR0
1337
144611
S872
T
A
L
A
Q
C
F
S
Q
L
G
E
H
P
P
Rat
Rattus norvegicus
NP_001099261
1271
136879
S801
T
A
L
A
Q
C
F
S
Q
L
G
E
H
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038667
1314
142462
G862
S
A
L
A
Q
C
F
G
Q
L
G
D
C
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35421
1354
148067
Y881
G
S
A
L
A
Q
A
Y
A
Q
Q
G
K
D
T
Honey Bee
Apis mellifera
XP_625036
1243
138433
V806
G
G
T
A
L
A
Q
V
Y
K
S
L
G
N
E
Nematode Worm
Caenorhab. elegans
Q19311
1343
148611
Y867
G
S
A
L
A
Q
V
Y
S
Q
I
G
D
D
C
Sea Urchin
Strong. purpuratus
XP_781955
1205
129101
I764
F
N
V
T
Q
D
L
I
T
D
G
L
L
T
A
Poplar Tree
Populus trichocarpa
XP_002315209
1377
150616
Q922
A
L
A
Q
A
F
G
Q
V
G
D
D
C
P
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M8D3
1387
151761
G933
S
A
L
A
Q
V
F
G
Q
I
G
N
D
C
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
97.1
87.5
N.A.
88.5
84
N.A.
N.A.
N.A.
N.A.
63.2
N.A.
50.5
50.1
47.5
52.4
Protein Similarity:
100
95.2
98
91.6
N.A.
92.8
88.6
N.A.
N.A.
N.A.
N.A.
75.1
N.A.
66
66.2
64.1
65.4
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
80
N.A.
6.6
6.6
6.6
20
Percent
Protein Identity:
50.3
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
65.2
N.A.
N.A.
65.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
62
24
70
24
8
8
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
54
0
0
0
0
0
0
16
8
8
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
8
16
16
16
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
8
% E
% Phe:
8
0
0
0
0
8
62
0
0
0
0
0
0
0
0
% F
% Gly:
24
8
0
0
0
0
8
16
0
8
70
16
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
0
8
62
16
8
0
8
0
0
54
0
16
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
62
% P
% Gln:
0
0
0
8
70
16
8
8
62
16
8
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
16
0
0
0
0
0
47
8
0
8
0
0
8
0
% S
% Thr:
47
0
8
8
0
0
0
0
8
0
0
0
0
8
8
% T
% Val:
0
0
8
0
0
8
8
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _